|
KMID : 1123920040180041169
|
|
Korean Journal of Oriental Physiology and Pathology
2004 Volume.18 No. 4 p.1169 ~ p.1172
|
|
|
Cytotoxic Activity of 13(E)-Labd-13-ene-8, 15-diol
|
|
Lim Jin-A
Kwang Jung-Sook
Yu Byung-Soo
Baek Seung-Hwa
|
|
|
Abstract
|
|
|
|
The cytotoxic activity of 13(E)-labd-13-ene-8α, 15-diol (1) was evaluated against tumor cell lines. A comparison of IC/sub 50/ values of this compound in cancer cell lines showed that their susceptibility to this compound decreased in the following order: P388>B16{F10>MDA-MB-231>A549>KB>SNU-C4 by the MTT method. 13(E}-Labd-13-ene-8α, 15-diol (1) was the most effective growth inhibitor of P388 murine leukaemia cell lines, producing approximately 8.3㎍/mL of IC/sub 50/ in the MTT method.
|
|
|
KEYWORD
|
|
|
Cytotoxicity, 13(E}-labd-13-ene-8, 15-diol (1), P388 murine leukaemia cell lines, MTT method
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
|